Drew ran a time of 52.38 to place himself 46th on the list. The top 48 advance to the NCAA Preliminary rounds.
"I am incredibly proud of how Derek Drew performed today," said SIUE Interim Head Coach Scott Block. "He had a come from behind win in the hurdles and hopefully qualified for the NCAA Championships. After receiving a cancer diagnosis, Derek made a conscious decision to not only thrive, but survive. His example is awe-inspiring."
Drew was crowned the OVC champion with his finish.
Several Cougars had big finishes in the meet, including Megan Lauzon with a third-place finish in the hammer throw after being crowned the OVC champion in the discus in day one. Lizzie Virgl finished second in the hammer.
"Megan had a great weekend and is someone we can always count on," said Block.
Julian Harvey took second in the triple jump after day one finishes of first and second in the long jump and high jump, respectively. Harvey broke his own record in the triple jump, finishing with a mark of 51-5.75.
"Julian once again proved why he is the Field Athlete of the Year," said Block.
The men and women both finished fifth overall in the championships. Eastern Illinois won the meet for the women while Southeast Missouri won for the men.
Several Cougars will go on to compete in the NCAA West Preliminaries May 27-28 in Lawrence, Kansas. The complete list will be released next week when all teams are finished with regular season competition.